Publications

Biology

• Heidebrecht F, Schulz I, Keller M, Behrens SE, Bader A (2009): Improved protocols for protein and RNA isolation from three-dimensional collagen sandwich culture of primary hepatocytes; Anal. Biochem. Oct 1; 393(1): 141-4
• Heidebrecht F, Heidebrecht A, Schultz I, Behrens SE, Bader A (2009): Improved semiquantitative Western blot technique with increased quantification range; J Immunol Methods Jun 30; 345(1-2): 40-8
• Heidebrecht F (2009): Etablierung und Charakterisierung einer polarisierten Kultur für Signaltransduktionsanalysen in primären murinen Hepatozyten (Establishment and Characterization of a polarized Culture for Signal Transduction Analyses in Primary Murine Hepatocytes), PhD Thesis, online publication at the University of Halle-Wittenberg Germany (urn:nbn:de:gbv:3:4-1941)
• Leal-Egaña A, Fritsch A, Heidebrecht F, Díaz-Cuenca A, Nowicki M, Bader A, Käs J (2012). Tuning liver stiffness against tumours: an in vitro study using entrapped cells in tumour-like microcapsules; J Mech Behav Biomed Mater. May; 9:113-21.
• Phanish MK, Heidebrecht F, Nabi ME, Shah N, Niculescu-Duvaz I, Dockrell ME (2014) The regulation of TGFβ1 induced fibronectin EDA exon alternative splicing in human renal proximal tubule epithelial cells.; J Cell Physiol. Jun 24.
• Phanish MK, Heidebrecht,F, Jackson M, Rigo F, Dockrell ME. (2024). Targeting alternative splicing of fibronectin in human renal proximal tubule epithelial cells with antisense oligonucleotides to reduce EDA+ fibronectin production and block an autocrine loop that drives renal fibrosis, Exp Cell Res. Sep 1;442(1):114186.

Psychology

• Heidebrecht, F, MacLeod, MB, Dawkins L (2018), Predictors of heroin abstinence in opiate substitution therapy in heroin-only users and dual users of heroin and crack, Addictive Behaviors, 77: 210–216.
• Heidebrecht, F, Macleod, MB (2019). Practitioners’ experience of working with dual users of heroin and crack cocaine. A Thematic analysis, Heroin Addiction and Related Clinical Problems, 21: 21-28.
• Heidebrecht F., Macleod M.B., and Dawkins L.(2022). Exploration of the physical health of dual users of heroin and crack in methadone treatment who inject or have previously injected drugs, Heroin Addiction and Related Clinical Problems, 24: 5-19.

Conference Posters and Talks (selection)

• F. Heidebrecht, I. Rode, J. M. Heinrich, A. Bader (2006): Investigating proliferation impairment in cultivated primary hepatocytes; The Annual TERMIS-EU Meeting, Rotterdam, The Netherlands;
• F. Heidebrecht, A. Heidebrecht, I. Rode, C. Schnepp, S Clauss, A. Bader (2007): Quantitative Western Blot for Systems Biology; 32nd FEBS Congress MOLECULAR MACHINES, Vienna, Austria;
• M Keller, F. Heidebrecht, I. Schulz, A. Bader (2007): Three dimensional culture model for polarized hepatocytes in a bioreactor; 3rd world congress on regenerative medicine „New Products for Diagnostics and Therapy“, Leipzig, Germany;
• F. Heidebrecht, I. Schulz, SE.Behrens and A. Bader (2008): Role of Endocytosis in Interleukin–6 Signalling in a Polarized Culture of Primary Hepatocytes; XX International Congress of Genetics, Berlin, Germany;
• F. Heidebrecht, MK. Phanish, SM. Freier, MEC. Dockrell (2012): Targeting Alternative Splicing of Fibronectin Rescues Cell Phenotype and Promotes Survival Following TGFβ Insult on Renal Epithelial Cells; 24th Annual Meeting of the European Renal Cell Study Group, Doorwerth, The Netherlands;
• S. Winn, F. Heidebrecht, I. Badshah, J. Reiser, M. Phanish, M. Dockrell (2012): CTGF Activation of Intracellular Signaling in Human Podocytes in Culture, UK Kidney Week, Gateshead, UK;
• F. Heidebrecht, MK. Phanish, SM. Freier, MEC. Dockrell (2012): Targeting Alternative Splicing of Fibronectin Rescues TGFβ1-induced Phenotypic Change in Human Tubule Cells; ASN Kidney Week, San Diego, CA, USA;
• F Heidebrecht, V Gnanananthan, B To, F Rigo, SM Freier, MEC Dockrell (2013): Modulating alternative splicing of fibronectin with antisense oligonucleotides; ASN Kidney Week, Atlanta, GA, USA.
• F. Heidebrecht, F. Rigo, SE. Freier, MEC. Dockrell (2014): Targeting Alternative Splicing of Fibronectin to Block an Autocrine Loop that Drives Renal Fibrosis; UK Kidney Week, Glasgow, UK. – Best-in-Group Poster award.
• RM Montero, F Heidebrecht, S Yates, D Makanjuola, MEC Dockrell (2014):The effects of a diabetic milieu on cytokines and fibrotic markers using a novel human in vitro co-culture system, UK Kidney Week, Glasgow, UK;
• T Crozier, L Driver and F Heidebrecht (2016) “AfterParty” a Chemsex service in East London, The European ChemSex Forum, London, UK.
• Heidebrecht, F, MacLeod, MB, Dawkins L (2017), Predictors of heroin abstinence in opiate substitution therapy in heroin-only users and dual users of heroin and crack, Second European Conference on Addictive Behaviour and Dependencies, Lisbon, Portugal and SSA Annual Conference Newcastle upon Tyne, UK.
• Heidebrecht, F, Macleod, MB. (2017) Practitioners’ experience of working with dual users of heroin and crack cocaine. A Thematic analysis, Second European Conference on Addictive Behaviour and Dependencies, Lisbon, Portugal and 2018 at EUROPAD, Krakow, Poland.
• Heidebrecht, F, Corless, J, MacLeod, MB, Dawkins L (2017), Exploration of the benefits of methadone treatment for dual users of heroin and crack who inject or have previously injected drugs – preliminary findings, Second European Conference on Addictive Behaviour and Dependencies, Lisbon, Portugal and SSA Annual Conference Newcastle upon Tyne, UK.
• Heidebrecht, F, Corless, J, MacLeod, MB, Dawkins L (2018). Predictors of poor health and heroin use in methadone-treated injecting heroin users: the importance of methadone dosage and crack cocaine use. EUROPAD, Krakow, Poland.
• Heidebrecht, F, Corless, J, MacLeod, MB, Dawkins L (2018). Differences in treatment outcomes by frequency and drug preference for dual users of heroin and crack in opiate substitution therapy – a pilot study. EUROPAD, Krakow, Poland.